Port Forwarding for websites?

i want to create a web-based business producing free-ware on the internet, a way of doing this i thought i could get my server (this is just going to be hosting the site) and hook it up through ethernet and portforward port 80 to the servers static ip address. The server software i wish to use is WAMP server 2. Also i will be hosting a private mail server with hmailserver and squirrel mail webmail interface. I will have eset smart security 4 as my anti-vrus and firewall, (with an exeption to wamp server) so the question is - Is this a secure setup? could i get viruses and could my data on my other computers on the network get hacked?